- Scarlet Oaks
- Scenic Hill
- Schildmeier Park
- Schley
- Schnellville
- Schooler Point Landing
- Scipio
- Scipio
- Scipio, Franklin
- Scircleville
- Scotchtown
- Scotland
- Scott
- Scott City
- Scott Corner
- Scottsburg
- Scottsville
- Seafield
- Searcy Crossroads
- Sebastian Island
- Sedalia
- Sedan
- Sedley
- Self Island
- Selvin
- Servia
- Sevastopol
- Seven Springs
- Sevenmile Island
- Sexton