S
- (Sarah Baartman District Municipality) Sunland
- (Chris Hani District Municipality) Sundwane
- (Amathole District Municipality) Sunduza
- (Nelson Mandela Bay Metropolitan Municipality) Summerstrand
- (Joe Gqabi District Municipality) Summer Pride
- (OR Tambo District Municipality) Sulenkama
- (Alfred Nzo District Municipality) Sugarbush
- (Sarah Baartman District Municipality) Studtis
- (Joe Gqabi District Municipality) Strydfontein (2)
- (Chris Hani District Municipality) Strathfield
- (Sarah Baartman District Municipality) Stormsriviermond
- (Sarah Baartman District Municipality) Stormsrivier
- (Chris Hani District Municipality) Stormberg
- (Chris Hani District Municipality) Stoney Croft
- (Joe Gqabi District Municipality) Stoneycroft
- (Joe Gqabi District Municipality) Stoneleigh
- (Chris Hani District Municipality) Stokwes Basin
- (Amathole District Municipality) Stockton
- (Joe Gqabi District Municipality) Stockton
- (Chris Hani District Municipality) Stockdale
- (Joe Gqabi District Municipality) Stinkord
- (Joe Gqabi District Municipality) Stillerust
- (Sarah Baartman District Municipality) Steytlerville
- (Joe Gqabi District Municipality) Steynsrust
- (Joe Gqabi District Municipality) Steynsnek
- (Joe Gqabi District Municipality) Steynsburg
- (Joe Gqabi District Municipality) Stewarton
- (Joe Gqabi District Municipality) Stevnsrus
- (Chris Hani District Municipality) Sterling Park
- (Chris Hani District Municipality) Sterkstroom